MODULATION OF HEMODYNAMICS AND CARDIAC ACTIVITY BY HYDROCOTYLE BONARIENSIS LEAF EXTRACTS IN RABBITS
By Komlan Mawuko Dosseh
Research Article
MODULATION OF HEMODYNAMICS AND CARDIAC ACTIVITY BY HYDROCOTYLE BONARIENSIS LEAF EXTRACTS IN RABBITS
ISSN: 3067-3313
DOI Prefix: 10.5281/zenodo.
Abstract
Cardiovascular disease (CVD) remains a significant contributor to global mortality, with 17.9 million deaths reported in 2019, accounting for nearly one-third of all global mortalities. Alarmingly, the burden of CVD disproportionately affects low- and middle-income nations, where over three-quarters of CVD-related deaths occur, with 82% of these fatalities transpiring prematurely before the age of 70 (WHO, 2017). Within the West African region, the prevalence of CVD varies widely, ranging from 12% to 69%, highlighting the urgent need for targeted interventions (Kearney et al., 2005; WHO, 2005). Hypertension, a major risk factor for CVD, stands as a prevalent and pressing concern, significantly contributing to the burden of disease. For instance, in Togo, hypertension prevalence reached 36.7% in 2012 within the commune of Lomé (Yayehd et al., 2013). Moreover, despite advancements in modern medicine, traditional remedies remain the primary form of healthcare for approximately 80% of the population in Africa and Asia, emphasizing the importance of understanding and integrating traditional practices within healthcare systems to address the complex challenges posed by CVD